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<i>Lophira alata<_i> Banks ex C.F.Gaertn.

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

12

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N4309A
    Lotusine hydroxide

    		Others Cardiovascular Disease
    Lotusine (hydroxide) is a pure alkaloid extracted from the green seed embryo of Nelumbo nucifera Gaertn. Lotusine (hydroxide) shows effects on the action potentials in myocardium and slow inward current in cardiac Purkinje fibers .
    Lotusine hydroxide
  • HY-N2666
    5α-Hydroxycostic acid

    		VEGFR Cancer
    5α-Hydroxycostic acid, a eudesmane-type sesquiterpene, is isolated from the herb Laggera alata. 5α-Hydroxycostic acid inhibits angiogenesis and suppresses breast cancer cell migration through regulating VEGF/VEGFR2 and Ang2/Tie2 pathways .
    5α-Hydroxycostic acid
  • HY-N6260
    4-O-beta-Glucopyranosyl-cis-coumaric acid

    		Others Others
    4-O-beta-Glucopyranosyl-cis-coumaric acid is a natural compound isolated formn Nelumbo nucifera Gaertn.
    4-O-beta-Glucopyranosyl-cis-coumaric acid
  • HY-N11164
    Mbamiloside A

    		Others Others
    Mbamiloside A (compound 4), an isoflavonoid derivative, is a nature product that could be isolated form the stem heartwood of Lophira alata .
    Mbamiloside A
  • HY-RS01362
    BANK1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    BANK1 Human Pre-designed siRNA Set A contains three designed siRNAs for BANK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    BANK1 Human Pre-designed siRNA Set A
    BANK1 Human Pre-designed siRNA Set A
  • HY-N4261
    Dehydronuciferine

    		Cholinesterase (ChE) Metabolic Disease
    Dehydronuciferine is isolated from the leaves of Nelumbo nucifera Gaertn, a acetylcholinesterase (AChE) inhibitor with an IC50 of 25 μg/mL .
    Dehydronuciferine
  • HY-N1239
    Sitoindoside I

    Longiside B; Sitoindoside; Daucosterol 6'-O-palmitate
    Sitoindoside I (Longiside B; Sitoindoside; Daucosterol 6'-O-palmitate) is a compound that can be isolated from Gyn'nops walla Gaertn .
    Sitoindoside I
  • HY-N5014
    Liensinine perchlorate
    Maximum Cited Publications
    8 Publications Verification

    		 Apoptosis Inflammation/Immunology Cancer
    Liensinine Perchlorate is a constituent of Nelumbo nucifera Gaertn, with ani-hypertension and anti-cancer activities. Liensinine Perchlorate induces colorectal cancer (CRC) cell apoptosis .
    Liensinine perchlorate
  • HY-N4309
    Lotusine

    		Others Cardiovascular Disease
    Lotusine is a pure alkaloid extracted from the green seed embryo of Nelumbo nucifera Gaertn. Lotusine shows effects on the action potentials in myocardium and slow inward current in cardiac Purkinje fibers .
    Lotusine
  • HY-N1963
    Curzerene

    Curzerene is a sesquiterpene is isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity. Curzerene inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression. Curzerene induces cell apoptosis .
    Curzerene
  • HY-N1510
    Kaempferol 3-O-gentiobioside

    		Glucosidase Metabolic Disease
    Kaempferol 3-O-gentiobioside is a flavonoid isolated from C. alata leaves with antidiabetic activity. Kaempferol 3-O-gentiobioside possesses activity against α-glucosidase and displays carbohydrate enzyme inhibitory effect with an IC50 of 50.0 µM .
    Kaempferol 3-O-gentiobioside
  • HY-N0484
    Liensinine
    Maximum Cited Publications
    8 Publications Verification

    		 Autophagy Mitophagy Apoptosis Cardiovascular Disease Cancer
    Liensinine is an autophagy/mitophagy inhibitor. Liensinine, a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn, has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc .
    Liensinine
  • HY-N0057
    3,4-Dicaffeoylquinic acid
    2 Publications Verification

    3,4-Di-O-caffeoylquinic acid; Isochlorogenic acid B

    		 Glucosidase Influenza Virus Apoptosis Endogenous Metabolite Infection Cancer
    3,4-Dicaffeoylquinic acid (3,4-Di-O-caffeoylquinic acid), naturally isolated from Laggera alata, has antioxidative, DNA protective, neuroprotective and hepatoprotective properties. 3,4-Dicaffeoylquinic acid exerts apoptosis-mediated cytotoxicity and α-glucosidase inhibitory effects. 3,4-Dicaffeoylquinic acid possesses a unique mechanism of anti-influenza viral activity, that is, enhancing viral clearance by increasing TRAIL .
    3,4-Dicaffeoylquinic acid
  • HY-N0485
    Liensinine Diperchlorate
    Maximum Cited Publications
    8 Publications Verification

    		 Autophagy Mitophagy Cardiovascular Disease
    Liensinine Diperchlor​ate is a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn. Liensinine Diperchlor​ate inhibits late-stage autophagy/mitophagy through blocking autophagosome-lysosome fusion. Liensinine Diperchlor​ate has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc .
    Liensinine Diperchlorate
  • HY-N0058
    4,5-Dicaffeoylquinic acid
    4 Publications Verification

    Isochlorogenic acid C

    		 HBV Endogenous Metabolite Apoptosis Glucosidase Infection
    4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) is an antioxidant, can be isolated from Gynura divaricata and Laggera alata. 4,5-Dicaffeoylquinic acid reduces islet cell apoptosis and improves pancreatic function in type 2 diabetic mice, and has obvious inhibitory activities against yeast α-glucosidase. 4,5-Dicaffeoylquinic acid inhibits prostate cancer cells through cell cycle arrest. 4,5-Dicaffeoylquinic acid also has anti-apoptotic, anti-injury and anti-hepatitis B virus effects .
    4,5-Dicaffeoylquinic acid

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